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br System description and data collection Fig shows the arra
2021-08-13

System description and data collection Fig. 1 shows the arrangement of the system studied. It provided cooling glycosylase to maintain thermal conditions in an institutional building. The locations of the measured variables (, and ) relating to temperature and flow rate are indicated in Fig. 1. T
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dhfr inhibitors COMT protein expression was investigated
2021-08-13

COMT protein dhfr inhibitors was investigated as a potential mechanism by which tolcapone may differentially affect male and female P and Wistar rats. COMT protein levels in the PFC were lower in P rats compared to Wistars but female P rats expressed greater levels of COMT in the PFC relative to mal
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Nevirapine To better understand the mechanism of splicing in
2021-08-13

To better understand the mechanism of splicing in CLCN1, we began by constructing a minigene spanning exons 5–7 of CLCN1, resulting in the synthetic CLCN1 (5–7) minigene. We also established a new assay using real-time reverse transcription (RT)-PCR, which can distinguish between splicing variants b
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Astrocytes play a key role in the brain as these
2021-08-13

Astrocytes play a key role in the brain, as these cells are involved in fluid, ion, pH, and neurotransmitter homeostasis, synapse function, energy and metabolism and blood-brain barrier (BBB) maintenance (Sofroniew and Vinters, 2010). PA is able to activate different damaging responses in astrocytes
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SANT-1 Primary renal PNET was first reported by
2021-08-13

Primary renal PNET was first reported by Seemayer et al in 1975. The possible etiology of rPNET is based on the theory of neural cell intussusception in the kidney during development that initiates the tumorigenesis. rPNET most commonly affects young adults, with a mean age of 30.4 years and male pr
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Enzyme selectivity of many enzymes like galactosidases acyla
2021-08-12

Enzyme selectivity of many Kaempferol-3-rutinoside like β-galactosidases, acylases, epoxyhydrolases, lipases, etc. has also been modulated by using different immobilization techniques. It can result in the selection of optimal biocatalyst for different processes. This has many advantages over strat
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br Oxidoreductase like MEM for prodrug activation br
2021-08-12

Oxidoreductase-like MEM for prodrug activation Future outlook Although MEM-mediated prodrug activation has been performed by different MEMs and prodrugs, and their effectiveness have been proved in vivo, only a few types of MEMs or prodrugs have been explored in prodrug activation until now [2
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br Material and methods br Results
2021-08-12

Material and methods Results and discussion Conclusion The gene encoding the Bos taurus muscle enolase enzyme was successfully isolated and cloned in this study. Optimization of the cloning, gene ticarcillin and purification was performed and protein elution at 95% purity was achieved. An
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Despite a high affinity for progesterone and a
2021-08-12

Despite a high affinity for progesterone and a relatively high affinity for testosterone [7], the binding of progesterone and testosterone to CBG is often disregarded [1], [2], [3]. However, the concentrations of these two hormones varies considerably under both normal physiological and pathophysiol
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Using the juxtarenal PPE the induction of
2021-08-12

Using the juxtarenal PPE, the induction of juxta- and suprarenal aneurysms is described herein (Fig. 3A). The infra-/suprarenal part of the thorough can now be investigated separately, taking into account different embryological backgrounds and varying reactivity to differing stimuli (reviewed by L
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br Experimental Procedures br Author
2021-08-12

Experimental Procedures Author Contributions Acknowledgments Introduction Germinal centers (GCs) form in secondary lymphoid organs of vertebrates in response to challenge with T-cell-dependent antigens. After extrafollicular and follicular interactions with cognate antigen and T helper c
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With respect to the muscle compartment only
2021-08-12

With respect to the muscle compartment, only low protein expression of ASB9 has been detected in healthy human skeletal muscle [as reported in the Human Protein Atlas (HPA)], whereas high levels of Asb5 protein expression are detected in mammalian skeletal muscle, which appears to be important in th
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br Patients and Methods Patients who had been initiated on
2021-08-12

Patients and Methods Patients who had been initiated on a DPP-4 inhibitor (see in the online version at doi:10.1016/j.clinthera.2018.06.002) between April 2012 and June 2017, when the common threshold for dose adjustment for all non-linagliptin DPP-4 inhibitors was a creatinine clearance (CrCl)
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BR stimulated PA formation via the DGK pathway
2021-08-12

BR-stimulated PA formation via the DGK pathway might have many effects in regulation of cell metabolism. For example, PA originated from DGKs pathway plays important roles in activation of NADPH oxidases, thus turning on ROS signaling [23]. PA is also connected to regulation of respiration processes
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p is a tumor suppressor
2021-08-12

p16 is a tumor-suppressor gene that inhibits cyclin-dependent kinase 4 and 6 activities and arrests the L-Mimosine in the G1 phase. Aberrant methylation and mutation of p16/MTS1 in OSCC of patients was found in our previous study. Moreover, the frequency of hypermethylation of p16 from the present
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