• br Conclusion br Introduction Giant cell tumors GCTs of the

  2018-11-06

  

  Conclusion Introduction Giant cell tumors (GCTs) of the bone account for 5% of all primary bone tumors. A GCT usually arises in the metaphyseal region of the long bones (e.g., distal femur, proximal tibia, distal radius), but it is rare in the cranium. It most often occurs at the age of 30–40

• FRAP assay measures the reducing ability

  2018-11-06

  

  FRAP assay measures the reducing ability of antioxidants against oxidative effects of reactive oxygen species. The antioxidant potential is estimated by ability of anti-oxidants to reduce TPRZ-Fe (III) complex to TPTZ-Fe (II). Total antioxidant power may be considered analogous to total reducing pow

• Because cathepsins are located within lysosomes

  2018-11-06

  

  Because cathepsins are located within lysosomes and can be targeted by BA1, and because they participate in many cell death pathways, they are attractive candidates as effectors of charontosis in mESCs (Broker et al., 2004; Droga-Mazovec et al., 2008; Hsu et al., 2009; Kagedal et al., 2001; Zuzarte-

• br Acknowledgments This work was supported by

  2018-11-06

  

  Acknowledgments This work was supported by the Major Research Plan of the National Natural Science Foundation of China (Grant No. 91129718), the National Natural Science Foundation of China (Grant no. 31140063, 81000181, 81272481, and 81071421), the Scientific and Technological Supporting Program

• br Methods br Results br Conclusion br Author

  2018-11-06

  

  Methods Results Conclusion Author contributions The following are the supplementary data related to this article. Acknowledgments Stemformatics is funded by a grant from the Australian Research Council Special Initiative in Stem Cell Science to CAW through Stem Cells Australia. Stemf

• These data provide new insight

  2018-11-06

  

  These data provide new insight into potential mechanisms by which CXCL10 contributes to demyelinating diseases. Early studies revealed that CXCL10 was produced in active lesions in patients with the demyelinating disease MS and CXCR3-positive T lymphocytes were enriched within the cerebral spinal fl

• br Materials and methods br Results br

  2018-11-06

  

  Materials and methods Results Discussion Heat shock, one of environmental factors, induces HSFs, leading to induction of HSPs involved in stress responses. In human and mouse ESCs, HSPs have been reported to be associated with self-renewal of ESCs by mediating folding and nuclear delivery o

• In this study we investigated

  2018-11-06

  

  In this study, we investigated the cellular and molecular features of p-NSCs, derived from mouse ESCs via “default mechanism”, a method that was reported to enrich p-NSC (Tropepe et al., 2001; Smukler et al., 2006; Rowland et al., 2011). We showed that p-NSCs have a decreased G2/M population compare

• A number of important differences

  2018-11-06

  

  A number of important differences in gene expression occurred with prolonged BMSC passage. Stem cell related genes, including Wnt and Notch signaling genes, were down-regulated in late passage cells. In addition, genes involved with DNA replication, recombination and repair, cell cycle, chromatin mo

• Over the last decade a number of studies have proposed

  2018-11-06

  

  Over the last decade, a number of studies have proposed that the adult mammalian heart is not a terminally differentiated organ and is capable of turning over cardiomyocytes throughout life and following injury (Porrello and Olson, 2010). The most compelling evidence for this radical concept comes f

• br Materials and methods br Verification of

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  Materials and methods Verification of karyotype Acknowledgments This project was funded by the Department of Biotechnology, Government of India (grant no. BT/IN/Denmark/31/MSI/2013) and the Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore. Resource Table: Resource d

• Cell adhesion molecules CAMs are transmembrane proteins that

  2018-11-06

  

  Cell adhesion molecules (CAMs) are transmembrane proteins that are responsible for mediating adhesion of cells to other cells and/or the extracellular matrix via their extracellular domains, while their intracellular domain interacts with the cytoskeleton. Thus, CAMs provide a direct link between th

• However although our pacemaker cells formed

  2018-11-06

  

  However, although our pacemaker GSK343 cost formed a synchronized and rapidly beating syncytium, and were capable of electrically connecting to and pacing ventricular slice cultures ex vivo, their potential to robustly engraft intramyocardially and to pace at physiological beating rates needs to be

• br Experimental Procedures br Author Contributions br Acknow

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  Experimental Procedures Author Contributions Acknowledgments Introduction The embryonic Apicidin gonad mesonephros (AGM) region is an important site of hematopoietic stem cell (HSC) development prior to colonization of the fetal liver (Dzierzak and Speck, 2008; Medvinsky et al., 2011).

• It should be noted that even in

  2018-11-05

  

  It should be noted that even in a high-resistance material like zinc oxide, there are areas with unstable I–V curves (see Fig. 9). Most of these areas are situated at the grain boundaries of the polycrystalline material. Furthermore, ZnO as a phase of variable composition exhibits “memristive” effe

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