• The results on the oxidative imbalance after mercury intoxic

  2018-10-29

  

  The results on the oxidative imbalance after mercury intoxication corroborates with many studies showing elevated values of MDA with decreased GSH contents in kidney and other tissues [9,15]. In a significant report blood is shown to reflect tissue oxidative stress with respect to MDA and GSH [19].

• Introduction Using the cell surface marker CD Yin

  2018-10-29

  

  Introduction Using the cell surface marker, CD133 (Yin et al., 1997; Yu et al., 2002), we identified a subpopulation of cells from a variety of human Nilotinib tumors, termed brain tumor initiating cells (BTICs), which exhibit stem cell properties in vitro (Singh et al., 2003; Reynolds and Weiss,

• Introduction Human embryonic stem cells HESCs can differenti

  2018-10-29

  

  Introduction Human embryonic stem abnormal lipid metabolism (HESCs) can differentiate into the three embryonic germ layers and have the potential to develop into every cell in the human body (Thomson et al., 1998). In order to enable the clinical practice of HESC cell therapy it is essential to und

• br Experimental Procedures br Acknowledgments This

  2018-10-29

  

  Experimental Procedures Acknowledgments This work was supported by funding from PyBOP ICR. F.B.A. was supported by the Erasmus Work Placement Programme. We thank Drs. Taiping Chen (MD Anderson Cancer Center) for providing J1 WT and Dnmt1-null ESCs and Masaki Okano (Riken) for providing TKO ESC

• br Results br Discussion Recent advances enabling the prospe

  2018-10-29

  

  Results Discussion Recent advances enabling the prospective isolation of mouse satellite (-)-JQ1 have facilitated mechanistic analyses of their myogenic function. For example, the ability to clonally sort satellite cells with high purity made possible the demonstration that these cells can un

• Besides IL RCC and RAEB t MDS DKK

  2018-10-26

  

  Besides IL6 (RCC- and RAEB(t)-MDS), DKK3 (RCC-MDS), CRLF1 and DAPK1 (RAEB(t)-MDS) were differentially expressed by MSCs of healthy controls versus MDS. DKK3 and CRLF1 have been associated with increased cell survival by suppressing apoptosis in MSCs and neuroblastoma cells, respectively (Song et al.

• Recent methods of reprogramming human fibroblasts to iNSCs

  2018-10-26

  

  Recent methods of reprogramming human fibroblasts to iNSCs employed genome-integrating lentiviral or retroviral vectors (Kumar et al., 2012; Ring et al., 2012), which may produce insertional mutations and residual or reactivation of transgenes. We used oriP/EBNA-1 episomal vectors to deliver reprogr

• We sought to determine whether T

  2018-10-26

  

  We sought to determine whether T cell-derived iPSCs (TiPSCs) could be used to analyze neurological diseases. Several issues regarding the utilization of TiPSCs in neurological studies remain unresolved. First, previous studies indicated that each iPSC clone retains an epigenetic memory relating to t

• Genome wide screens have identified many potential regulator

  2018-10-26

  

  Genome-wide screens have identified many potential regulators of stem cell function. These include genes with established roles in transcription regulation, cell growth, and differentiation, as well as genes whose function is largely unknown or remains to be validated in the context of stem cell bio

• In comparison little is known

  2018-10-26

  

  In comparison, little is known about the glucose-induced Ca2+ signaling ability of less mature pancreatic progenitors. One such study by Basford et al. (2012) demonstrated that >80% of insulin+ cells, derived from hESCs via a 22-day in vitro differentiation protocol (S5), increased intracellular Ca2

• Scanners with LIDE LED indirect exposure are an improved ver

  2018-10-26

  

  Scanners with LIDE (LED indirect exposure) are an improved version of the CIS technology. Here the light source uses powerful tri-color RGB (Red, Green, Blue) LEDs, and the radiation is directed to the object via quartz fibers ensuring uniform exposure over the entire width of the original scanner w

• We were concerned about confounding by individual SES

  2018-10-26

  

  We were concerned about confounding by individual SES in a zip code-matched case-control study of 13-valent pneumococcal conjugate vaccine (PCV13) effectiveness (Moore et al., 2016). PCV13 was licensed for use in children in the US in February 2010 and replaced the effective, but more limited, 7-val

• In sum even though prisons are theoretically a

  2018-10-26

  

  In sum, even though prisons are theoretically a neutralizing force for health, the varying etiologies of health conditions interact with the prison context differently. Moreover, there is a racialized and gendered health selection process into prison. All inmates are drawn from unhealthy segments of

• aa-utp The results of hazard models estimating differences i

  2018-10-26

  

  The results of hazard models estimating differences in mortality among Hispanic subgroups by region of origin and nativity are shown for men in Table 3. The first two models consider men aged 25–64. Model 1 adjusts only for age and year of interview (unadjusted model), while Model 2 includes socioec

• An individual can maintain various

  2018-10-26

  

  An individual can maintain various social identities simultaneously, and one will stand out among the rest when the combination of personal and situational characteristics propitiate the ‘depersonalization’ of personal identity. Depersonalization “does not insinuate a negative connotation in the sen

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