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Second governments can play an important
2019-04-18

Second, governments can play an important part in providing incentives for industry to invest in discovering new uses for old drugs. For example, it dna-pk pathway could consider the extension of patent protection for old drugs that have found new uses, for example, as embodied in the Hatch-Waxman
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Perhaps counter intuitively the most strategic tobacco contr
2019-04-18

Perhaps counter-intuitively, the most strategic tobacco control policies to reduce adolescent smoking and secondhand smoke exposure in LMICs may not be those targeting adolescents. Targeted campaigns can be expensive, and are unlikely to be as effective as the more affordable tobacco control policie
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proton pump inhibitors Although a wealth of studies tracking
2019-04-18

Although a wealth of studies tracking ODA+ have been done, few have provided in-depth study of how ODA+ in reproductive, maternal, newborn, and child health affects health outcomes, and to what extent the long-term goal of donors has been achieved through aid programmes. This panel dataset opens the
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Coincidente con esta perspectiva Tadeo es un
2019-04-18

Coincidente con esta perspectiva, Tadeo es un escritor que busca alejarse del vulgo y considera que la gran literatura no puede ser comprendida por todos. Su ensimismamiento lo conduce al desprecio por los otros y Exendin-4 un aislamiento extremo, donde al final ni siquiera es capaz de cubrir sus ne
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br D microCT data Bone volume BV TV
2019-04-18

3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular CMX001 (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published in the lite
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br Conflict of interest br Acknowledgments This
2019-04-18

Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne
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br La profesionalizaci n del poeta como un
2019-04-18

La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonanz
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OS is Executive Director of the
2019-04-18

OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun
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Asimismo el texto convoca a cuestionar muchos de los mitos
2019-04-18

Asimismo, el texto convoca tryptophan hydroxylase cuestionar muchos de los mitos sobre la guerra civil en Guatemala. No fue durante los años setenta que los revolucionarios guatemaltecos volcaron su mirada sobre el componente indígena como parte de las fuerzas insurgentes, tampoco fue en los ochenta
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Different ideas however emerged in the s and s
2019-04-17

Different ideas, however, emerged in the 1960s and 1970s in the minds of computational biologists interested in the theory of wave propagation in excitable media. Based on chemical [17] and numerical experiments, [18] scientists in the Soviet Union and the USA began to suggest that fibrillation was
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The PPI from the CS ostium was close to the
2019-04-17

The PPI from the CS ostium was close to the TCL, suggesting that the CS ostium was on the dominant circuit (Fig. 8B). During entrainment from the CS ostium, the last captured beat of the TA was the second beat after the stimulus, suggesting that the slow conduction area (crosshatch) was located dist
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br Results As shown in Table the amplitude and
2019-04-17

Results As shown in Table 1, the amplitude, and the onset or the end of LA potentials were successfully determined via visual inspection. Among 19 patients with AP, LA potentials were detected in 7 (37%), all in an LA → CSM activation sequence (Fig. 2). In contrast, among 21 patients with CCW AFL
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br Alcohol and adipose tissue insulin
2019-04-17

Alcohol and adipose tissue insulin resistance, inflammation, and lipolysis Insulin is a hormone produced by pancreatic beta cells. It mediates carbohydrate, lipid, and protein metabolism in multiple organs, including the liver, adipose tissue, and skeletal muscle, to utilize and store azidothymid
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Pregnancies in adolescents year olds and in older women year
2019-04-17

Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent GSK503 since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births occurring in
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El libro de William Crawford publicado en traducido
2019-04-17

El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl
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